Aqumeldi® is indicated for the treatment of heart failure in children from birth to less than 18 years1
Key Administration Information:
- Removes the need to adapt adult formulations.2-4
- Each mini orodispersible tablet is 2mm in size and contains 0.25mg of enalapril maleate1
- Can be administered once or twice daily1
- Rapidly disperses in the mouth without the need for water2
- Multiple orodispersible tablets can be administered at the same time5,6
- Can be administered through feeding tubes when dispersed1
- 100 day expiry, once opened1
Key Dosing Information1
Please refer to the full SmPC before prescribing; including special populations dosing (e.g. renal impairment).
Starting/test dose: 0.01 to 0.04 mg/kg (max 2mg) as a single initial dose
Target/maintenance dose: 0.15 to 0.3 mg/kg (max 20 mg) per day in one or two divided doses. The dose should be individualised according to blood pressure, serum creatinine and potassium response.
Guidance on doses under 0.25mg: Doses less than 0.25mg can be achieved by placing one 0.25mg tablet in a 10ml oral syringe, adding tap water (sterile water if <6months) to the 10 ml graduation, rolling the syringe for 3 minutes to fully disperse the tablet and administering the required volume immediately to the patient (1ml will contain 0.025mg enalapril).
Aqumeldi® is now listed in the BNFC7