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One size doesn’t fit all

Aqumeldi® is indicated for the treatment of heart failure in children from birth to less than 18 years1

Aqumeldi® is an innovative formulation and the first and only paediatric-licensed enalapril ODT for heart failure — because children are not just small adults2-4

Aqumeldi® is an innovative paediatric formulation — a mini ODT that rapidly disperses in the mouth2

Aqumeldi® is readily available in a low dose strength (0.25 mg) — enabling accurate titration and dose adjustments1,2

Aqumeldi® - dedicated paediatric clinical studies in HF establishing its safety profile over a duration of 1 year1,5

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References

1.   Aqumeldi Summary of Product Characteristics, (January 2024)
2.  Bajcetic, M., et al., (2019). Orodispersible minitablets of enalapril for use in children with heart failure (LENA): Rationale and protocol for a multicentre pharmacokinetic bridging study and follow-up safety study Contemporary Clinical Trials Communications. Vol 15:100393
3.  Klassen, T.P., et al. (2008). Children are not just small adults: the urgent need for high quality trial evidence in children. PLOS Medicine. Vol 5(8):e172.
4.  British National Formulary for Children (BNFC). Enalapril maleate. Available from:https://bnfc.nice.org.uk/drugs/enalapril-maleate/  
5.  Data on file

UK-ENA-24-0039 | January 2025

Adverse Event Reporting Information

UK: Adverse events should be reported. Reporting forms and information can be found at: www.mhra.gov.uk/yellowcard. 

Republic of Ireland: Adverse events should be reported. Reporting forms and information can be found at: www.hpra.ie.

Adverse events should also be reported to Proveca Limited. Phone: +44 333 200 1866 E-Mail: medinfo@proveca.com

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